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发布日期:2014-04-23
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牛东红 教授


牛东红,女,博士,教授,硕士生导师。2001年毕业于河北大学生物学专业,理学学士;2004年毕业于河北大学水生生物学专业,理学硕士;2009年毕业于上海海洋大学水产养殖学专业,博士学位。于2010-2011年和2017-2018年在美国Auburn University农学院水产系遗传学实验室进行留学访问,期间主要开展水产动物分子生物学与基因组学等相关科研工作。目前,主讲本科生课程《遗传学》,并获得“遗传学”好课堂,曾多次获得遗传学相关教学比赛奖,担任“卓越班学生导师。在科研方面,主要从事海洋贝类遗传育种与基因组学方向的科研工作,主持国家自然科学基金2项,入选学校 “三海人才”计划,为中国水产学会、动物学会、贝类学分会会员,担任国家自然科学基金一审评审专家,上海市高水平地方高校创新团队和江苏省高校协同创新中心骨干,发表科研论文四十余篇,获得国家水产新品种1个。

  

一、主要承担的科研项目:

[1]2018.01-2020.12水产双一流学科建设项目水产种质资源研究与支撑平台能力提升

[2]2015.01-2018.12 国家自然科学基金-面上项目 “缢蛏幼虫变态过程中IGFBPs基因调控的分子基础研究

[3]2016.01-12横向课题一种缢蛏家系的建立和良种选育方法技术转化与应用

[4]2013.01-2017.12水产动物遗传育种中心上海市协同创新中心项目缢蛏遗传育种服务团队

[5]2013.01-2016.12国家自然科学基金面上项目肺螺亚纲石磺科贝类由海洋向陆地及至淡水的进化生物学研究

[6]2012.01-2014.12 国家自然科学青年基金缢蛏生长相关基因SNPsCNPs与生长性状的关联分析

[7]2012.01-2015.12 国家“863”计划项目主要养殖双壳贝类良种培育子课题 “缢蛏良种培育

[8]2010.01-2012.12国家自然科学基金面上项目中国大陆沿海石磺科贝类形态结构比较及系统分类研究

[9]2010.01-2012.01上海市优秀青年教师选拔专项基金缢蛏群体的遗传结构研究

[10]2009.01-2011.12上海高校创新团队建设项目水产动物种质资源与创新

[11]2007.01-2010.12 国家“863”计划项目子课题缢蛏高产抗逆品种选育

二、主要发表的科研论文:

[1]Shumei Xie, Donghong Niu, Kanyun Wei, Zhiguo Dong, Jiale Li*, Polymorphisms in the FOXO gene are associated with growth traits in the Sanmen breeding population of the razor clam Sinonovacula constricta, Aquaculture and Fisheries, 2018,3(5) : 177-183

[2]Yuqi Bai, Donghong Niu*, Yulin Bai, Yan Li, Tianyi Lan, Maoxiao Peng,Jiale Li*. Identification of a novel galectin in Sinonovacula constricta, and its role in recognition of gram-negative bacteria. Fish & Shellfish Immunology. 2018,80:1-9

[3]杜蕴超#, 何圣耀, 谢淑媚, 牛东红*, 李家乐. 多巴胺受体拮抗剂对缢蛏多巴胺D2类受体的影响[J]. 基因组学与应用生物学, 2018:1-7.

[4]杜蕴超,谢淑媚,何圣耀,牛东红*, 李家乐. 缢蛏多巴胺受体基因及其在损伤修复中的作用[J].热带海洋学报,2018,37(03):45-54.

[5]Kanyun Wei, Donghong Niu*, Maoxiao Peng, Shumei Xie, Shentong Wang, Jiale Li. Characterization of two splice variants of EGFR and their effects on the growth of the razor clam [J]. Aquaculture and Fisheries, 2018,3(2): 62-31

[6]Donghong Niu, Ya Xiong, Maoxiao Peng, Xue Meng,Tianyi Lan, Jiale Li*. Hemolytic reactions in the hemolymph of bivalve Sinonovacula constricta show complement-like activity. Fish & Shellfish Immunology, 2018, 79, 11-17.

[7]Shumei Xie, Donghong Niu*, Yunchao Du, Kanyun Wei, Hai Dang Nguyen, Jiale Li. Expression and characterization of insulin-like growth factor II mRNA binding protein in the razor clam Sinonovacula constricta, Aquaculture and Fisheries, 2017, 2(6):247-255.

[8]Donghong Niu, Yunchao Du, Ze Wang, Shumei Xie, Hai-Dang Nguyen, Zhiguo Dong, Heding Shen, Jiale Li*. Construction of the first high-density genetic linkage map and analysis of quantitative trait loci for growth-related traits in Sinonovacula constricta[J]. Marine Biotechnology, 2017,19 (5):488–496.

[9]Maoxiao Peng, Donghong Niu, Zhiyi Chen, Tianyi Lan, Zhiguo Dong,Thi-Nga Tran, Jiale Li*. Expression of a novel complement C3 gene in the razor clam Sinonovacula constricta and its role in innate immune response and hemolysis. Developmental & Comparative Immunology, 2017, 73:184-192.

[10]王泽, 杜文俊, 陈氏娥, 董志国,牛东红*, 沈和定, 李家乐. 缢蛏微卫星多态性分析及其在亲子鉴定中的应用[J]. 上海海洋大学学报, 2016, 6:807-813

[11]Maoxiao Peng 1, Donghong Niu 1, Fei Wang, Zhiyi Chen, Jiale Li*. Complement C3 gene: Expression characterization and innate immune response in razor clam Sinonovacula constricta. Fish & Shellfish Immunology, 2016, 55: 223-232

[12]彭茂潇, 牛东红, 李家乐*. 海洋无脊椎动物补体系统研究进展[J]. 海洋渔业, 2016, 38(3):321-328

[13]Donghong Niu, Fei Wang, Shumei Xie, Fanyue Sun, Ze Wang, Maoxiao Peng, Jiale Li*. Developmental transcriptome analysis and identification of genes involved in larval metamorphosis of the razor clam, Sinonovacula constricta. Marine Biotechnology, 2016, 18(2):168-175.

[14]Donghong Niu1, Fei Wang1, Honggang Zhao, Ze Wang, Shumei Xie, Jiale Li*. Identification, expression, and innate immune responses of two insulin-like peptide genes in the razor clam Sinonovacula constricta. Fish & Shellfish Immunology.2016, 51:401-404

[15]Thi-Nga Tran 1, Dong-Hong Niu 1, Hai-Dang Nguyen, Shu-Mei Xie, Jia-Le Li*. Populations genetic structure of the razor clam Sinonovacula constricta from china, korea and vietnam.Biochemical Systematics and Ecology, 2015, 61: 429-436

[16]谢淑媚, 牛东红*, 阮海灯, 王泽, 王飞, 陈世娥, 李家乐. 缢蛏IGFBP基因结构及生长性状相关的SNP筛选., 水产学报,2015, 39(6): 799-809.

[17]Donghong Niu1, Lie Wang1, Zhiyi Bai, Shumei Xie, Honggang Zhao, Jiale Li.Identification and expression characterization of the myostatin (MSTN) gene and association analysis with growth traits in the razor clam Sinonovacula constricta. Gene, 2015, 555(2):297-304

[18]李多,杜文俊,牛东红,李家乐,沈和定,管菊,吕昊泽. 缢蛏家系早期生长表现比较[J]. 中国海洋大学学报2015, 39(6): 799-809. (自然科学版),2015,10:36-41.

[19]Donghong Niu, Shumei Xie, Zhiyi Bai, Lie Wang, Kai Jin, Jiale Li *.Identification, expression, and responses to bacterial challenge of the cathepsin C gene from the razor clam Sinonovacula constricta.Developmental and Comparative Immunology, 2014, 46(2): 241-245.

[20]Donghong Niu, Lie Wang, Fanyue Sun, Zhanjiang Liu, Jiale Li*. Development of molecular resources for an intertidal clam, Sinonovacula constricta using 454 transcriptome sequencing. PLoS ONE, 2013, 8(7): e674562013.

[21]Donghong Niu1, Kai Jin1, Lie Wang, Bingbing Feng, Jiale Li*. Molecular characterization and expression analysis of novel cathepsin L genes in the razor clam, Sinonovacula constricta. Fish and Shellfish Immunology, 2013, 35(2): 581-588.

[22]Donghong Niu1, Kai Jin1, Lie Wang, Fanyue Sun, Jiale Li*. Molecular characterization and expression analysis of cathepsin B gene in the razor clam, Sinonovacula constricta. Developmental & Comparative Immunology, 2013, 41(1): 94-99

[23]Lie Wang 1, Donghong Niu 1, Jiale Li *. Charaterization of novel EST-derived SNP markers by using 454 pyrosequencing in Sinonovacula constricta. Conservation Genetics Resources. 2013,5(1): 191-193.

[24], 牛东红, , 李家乐*. 缢蛏丝氨酸蛋白酶基因的序列特征及其表达分析[J]. 上海海洋大学学报, 2013, 22(4): 481-487

[25]Donghong Niu, Bingbing Feng, Dabo Liu , Yumin Zhong, Heding Shen, Jiale Li*. Significant genetic differentiation of 10 populations of the razor clam (Sinonovacula constricta) along the coast of China revealed by microsatellite analysis. Zoological Studies. 2012,51(3): 406-414

[26]Donghong Niu, Eric Peatman, Hong Liu, Jianguo Lu, Huseyin Kucuktas, Shikai Liu,Fanyue Sun, Hao Zhang, Tingting Feng, Zunchun Zhou, Jeffery Terhune, Geoff Waldbieser, Jiale Li, Zhanjiang Liu*. Microfibrillar associated protein 4 (MFAP4) genes in catfish play a nove lrole in innate immune responses. Developmental & Comparative Immunology, 2011, 35(5): 568-579 (SCI).

[27]牛东红, 冯冰冰, 李家乐*. 缢蛏铁蛋白基因的分子特性及其表达分析. 上海海洋大学学报, 2012, 21(5): 641-649

[28]牛东红, 刘达博, 陈慧, 冯冰冰, 林国文, 李家乐*. 缢蛏种群遗传多样性的周年变异分析.生物技术通报, 2012 (1):168-171.

[29]冯冰冰, 牛东红, 钟玉民, 陈慧, 林国文 , 李家乐*. 缢蛏ScHsc70 cDNA的分子特性和表达分析. 中国水产科学, 2012, 19(1): 1-12.

[30]牛东红, 冯冰冰, 刘达博, 沈和定, 李家乐* .浙闽沿海缢蛏群体遗传结构的微卫星和线粒体COⅠ序列分析. 水产学报, 2011, 35(12): 1806-1814.

[31]Zhiyi Bai, Donghong Niu, Jiale Li*. Development and characterization of EST-SSR markers in the freshwater pearl mussel (Hyriopsis Cumingii). Conservation Genetics Resource , 2011, 3 :765-767.

[32]冯冰冰, 钟玉民, 牛东红, 陈慧, 林国文 , 李家乐*. 缢蛏β-ACTIN 1 基因的分子特性及其表达分析. 水产学报, 2011, 35(5): 650-659.

[33]刘达博, 牛东红, 冯冰冰, 钟玉民, 李家乐*. 乐清湾和三沙湾缢蛏群体遗传多样性的微卫星分析. 上海海洋大学学报, 2011, 20(3): 350-357

[34]牛东红, 陈慧, 王树亮, 林国文, 李家乐*. 我国沿海缢蛏群体遗传结构的mtDNA-COⅠ分析. 动物学杂志, 2010, 45(2): 11-18

[35]牛东红, 陈慧, 林国文, 李家乐*. 缢蛏群体微卫星分析中样本量对遗传多样性指标的影响. 海洋科学进展, 2010, 2: 203-207.

[36]Runling Zheng, Jiale Li*, Donghong Niu. The complete DNA sequence of the mitochondrial genome of Sinonovacula constricta (Bivalvia: Solecurtidae). Acta Oceanologica Sinica, 2010, 29(2): 88-92.

[37]Bingbing Feng, Lingli Dong, Donghong Niu, Shanshan Meng, Bing Zhang, Dabo Liu, Songnian Hu*, Jiale Li*. Identification of immune genes of the agamaki clam (Sinonovacula constricta) by sequencing and bioinformatic analysis of ESTs. Marine Biotechnology, 2010, 12: 282–291.

[38]Shu-Liang Wang, Dong-Hong Niu, Ming-Jing Jia, Jia-Le Li*. Polymorphic microsatellite loci for population studies of Bullacta exarata. Conservation Genetics, 2010, 11: 1231-1233.

[39]牛东红, 李家乐*, 冯冰冰, 刘达博. 缢蛏六个群体遗传结构的ISSR分析. 应用与环境生物学报, 2009, 15(3): 332-336.

[40]刘达博, 牛东红, 姜志勇, 李家乐*. 缢蛏7群体的形态差异与判别分析. 海洋渔业, 2009, 31(4): 363-368.

[41]郑润玲, 李家乐*, 牛东红. 两种缢蛏线粒体基因全序列扩增方法的比较. 生物技术通报, 2009, 4: 119-121.

[42]Shu-Liang Wang, Dong-Hong Niu, Jia-Le Li*. Isolation and characterization of 10 polymorphic microsatellites in Meretrix meretrix. Conservation Genetics Resources, 2009, 1:111-113.

[43]贾名静, 李家乐*, 牛东红, 白志毅. 长江中下游褶纹冠蚌不同地理群体COI基序列变异分析. 动物学杂志, 2009, 44(1): 1-8.

[44]Niu D H, Li J L, Liu D B. Polymorphic microsatellite loci for population studies of the razor clam, Sinonovacula constricta[J]. Conservation Genetics, 2008, 9(5):1393-1394.

  

三、申请和授权专利:

[1]刘达博, 李家乐, 牛东红, 冯冰冰. 一种贝类育苗简易报警装置. 实用新型. 专利号2010206952157.0

[2]李家乐,王劦,牛东红,赵弘刚,谢淑媚,金凯。实用新型专利“一种用于缢蛏的育苗桶”申请时间:20121215日。实用新型. 授权时间:20131030日:专利号:ZL2012207239325.5

[3]李家乐,彭茂潇,牛东红,谢淑媚,黄文吉,王飞,王泽,卫侃韵,杜蕴超。一种防毒自动凝胶切割器和成像仪及其割胶方法。实用新型.申请日期:64日。专利号:201510300790.X

[4]牛东红, 李家乐, 沈和定,王劦,谢淑媚,李多,郑培,王飞,曾仕梅。一种缢蛏家系的建立和良种选育的方法. 发明专利. 申请时间:20131023. 授权时间:2015722. 专利号:ZL201310503970.9

[5]李家乐,彭茂潇,牛东红,谢淑媚,王飞,王泽,杜蕴超,黄文吉。一种实验用移液枪枪头快速摆放器. 实用新型. 申请时间:201564日。授权时间:20151028.专利号:ZL 201520378241.X

[6]李家乐,彭茂潇,牛东红,谢淑媚,王泽,王飞,卫侃韵。一种贝类体态快速批量数据测量仪。实用新型. 申请时间:201564日。授权时间:20151111日。专利号:ZL 201520378894.8

[7]李家乐,彭茂潇,牛东红,杜蕴超,卫侃韵,王飞,王泽。一种提取双壳贝类血淋巴的操作装置。实用新型. 申请时间:201616日。授权时间:2016622日。专利号:ZL 201620009773.0

[8]牛东红,杜蕴超,李家乐,谢淑媚。一种方便双壳贝类暂养换水和代谢废物排放的暂养箱。实用新型,申请时间:201719日,授权时间:201793日。专利号ZL 201720022932.5

  

四、联系方式

通讯地址:上海市沪城环路999号上海海洋大学水产与生命学院C303

电话:021-61900438

E-maildhniu@shou.edu.cn

(2018年11月更新)