牛东红，女，博士，教授，博士生导师。中国水产学会盐碱水养殖专业委员会委员。2001年毕业于河北大学生物学专业，理学学士；2004年毕业于河北大学水生生物学专业，理学硕士；2009年毕业于上海海洋大学水产养殖学专业，博士学位。曾于美国Auburn University农学院水产系遗传学实验室进行留学访问。主持国家自然科学基金项目、国家重点研发计划蓝色粮仓专项任务等项目。在Aquaculture、Marine Biotechnology、CBP、水产学报等水产海洋领域期刊发表论文50余篇，培育国家水产新品种1个。以第一完成人获得上海海洋科学技术奖一等奖以及全国高校教师教学创新大赛上海市二等奖。

主要研究方向

[1] 海洋贝类环境适应性进化机制。

[2] 海洋贝类耐盐耐高温等抗逆性状的调控机制。

[3] 海洋贝类分子育种关键技术探究与新品种遗传选育。

主要承担的省部级和国家级科研项目

[1] 2024.1-2027.12国家自然科学基金面上项目“脯氨酸提高缢蛏耐高盐性能的关键信号通路和作用机制”

[2] 2023.12-2027.12国家重点研发计划“盐碱水土一体化循环利用与生态改良渔业模式”项目

[3] 2021.1-2025.12 上海市水产动物良种创制与绿色养殖协同创新中心项目

[4] 2019.11-2022.12国家重点研发计划“海水池塘和盐碱水域生态工程化养殖技术与模式”项目

[5] 2019.11-2022.12国家重点研发计划“滩涂增养殖技术与生态农牧化新模式”项目

[6] 2018.01-2020.12 水产双一流学科建设项目“水产种质资源研究与支撑平台能力提升”

[7] 2015.01-2018.12 国家自然科学基金面上项目 “缢蛏幼虫变态过程IGFBPs基因调控的分子基础研究”

[8] 2012.01-2014.12 国家自然科学青年基金 “缢蛏生长相关基因SNPs和CNPs与生长性状的关联分析”

[9] 2012.01-2015.12 国家“863”计划项目“主要养殖双壳贝类良种培育”

近五年主要发表论文

[1] 牛东红, 王宏蕾, 李家乐*. 海洋贝类对盐度胁迫适应机制的研究进展.水产学报. 2024 DOI: 10.11964/jfc.20221013727

[2] Ziqi Guo, Yukuan Chen, Xinxin Du, Yifeng Li, Donghong Niu*. Ammonia induced oxidative stress triggered apoptosis in the razor clam (Sinonovacula constricta). Environmental Science and Pollution Research. 2024 https://doi.org/ 10.1007/s11356-024-32635-0

[3] Tao Liu, Yang Lu, Mengying Sun, Heding Shen*, Donghong Niu*. Effects of acute hypoxia and reoxygenation on histological structure. Fish and Shellfish Immunology.2024,145: 109310

[4] Yihua Chen，Min Deng，Zhiguo Dong, Yifeng Li, Donghong Niu*. Function of taurine and its synthesis-related genes in hypertonic regulation of Sinonovacula constricta. Comparative Biochemistry and Physiology Part A. 2024, 287:111536

[5] Yuting Han, Beibei Li, Yifeng Li, Donghong Niu*. The Inhibitory Effects of RNA-Interference-Mediated Guanylate Cyclase Knockdown on Larval Metamorphosis and Early Progeny Growth of Razor Clam. Genes,2023, 14(2):459

[6] 陈义华,牛东红*,董志国,李家乐. 缢蛏耐高盐性能及其与生长性状的相关性分析[J].海洋科学,2022,46(10):51-58.

[7] Yihua Chen, Xinin Du, Zhiguo Dong, Yifeng Li, Donghong Niu*. Heritability estimation of high salt tolerance in razor clam (Sinonovacula constricta) Aquaculture 2022: 738423

[8] Yihua Chen, Yukuan Chen, Liang Tao, Xinxin Du, Zhiguo Dong*, Donghong Niu*, Jiale Li*. Genetic parameters and genotype by environment interaction for growth traits of razor clam Sinonovacula constricta, from outdoor pond and semi-natural environment. Aquaculture Reports,2022,24:101173

[9] Yizhen Wang, Yuting Han, Yanhui Wang, Min Lv, Yifeng Li, Donghong Niu *. Expression of p38MAPK and its regulation of apoptosis under high temperature stress in the razor clam Sinonovacula constricta. Fish and Shellfish Immunology, 2022,12: 288-297

[10] Yihua Chen, Haoyu Li, Hongbing Ding, Zhiguo Dong, Donghong Niu*, Jiale Li*. Heritability estimation and path analysis for growth traits of the razor clam Sinonovacula constricta under high salinity. Aquaculture, 2021(545):737175

[11] Yinghan Wu, Yi Zheng, Yan Li, Yifeng Li, Donghong Niu*. Two fibrinogen-related proteins (freps) in the razor clam (Sinonovacula constricta ) with a broad recognition spectrum and bacteria agglutination activity. Developmental & Comparative Immunology, 2021,121.104075

[12] Yan Li, Donghong Niu*, Yinghan Wu, Zhiguo Dong, Jiale Li*.  Integrated analysis of transcriptomic and metabolomic data to evaluate responses to hypersalinity stress in the gill of the razor clam (Sinonovacula constricta). Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2021, 38(4):100793. 3

[13] Yihua Chen^#, Bo Ye^#, Donghong Niu*, Jiale Li. Changes in metabolism and immunity in response to acute salinity stress in Chinese razor clams from different regions, Aquaculture Reports, 2021(19),100624

[14] Zhi Li^#, Maoxiao Peng^#, Deborah Mary Power, Donghong Niu*, Zhiguo Dong, Jiale Li*. RNAi-mediated knock-down of the dopamine beta-hydroxylase gene changes growth of razor clams. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2021, (252):110534.

[15] Maoxiao Peng^#, Zhi Li^#, Xiaojun Liu, Donghong Niu*, Jiale Li*. Inland alkaline brackish water aquaculture of juvenile razor clam: Survival, growth, physiology and immune responses. Aquaculture Reports, 2020(18):100463.

[16] Donghong Niu, Beibei Li, Shumei Xie, Zhiguo Dong, Jiale Li*. Integrated mRNA and Small RNA Sequencing Reveals Regulatory Expression of Larval Metamorphosis of the Razor Clam. Marine Biotechnology, 2020(22): 696–705.

[17] Donghong Niu, Zhi Li, Yunchao Du, Shengyao He, Zhiguo Dong, Jiale Li*. Identification of a dopamine receptor in Sinonovacula constricta and its antioxidant responses. Developmental and Comparative Immunology. 2020(103): 1-7.

[18] Zhi Li, Donghong Niu*, Maoxiao Peng, Ya Xiong, Jie Ji, Zhiguo Dong, Jiale Li*. Dopamine beta-hydroxylase and its role in regulating the growth and larval metamorphosis in Sinonovacula constricta. Gene, 2020(737):144418.

获奖情况

2023.09  上海海洋大学育才奖

2022.08  上海海洋科学技术奖 一等奖

2021.11  神农中华农业科技奖 优秀创新团队

2022.08  全国高校教师教学创新大赛 上海市二等奖

2021.12  全国高校教师教学创新大赛 校级一等奖

2021.07  上海海洋大学优秀研究生指导教师

2019.12  汉宝奖学金优秀青年教师奖

2019.12  上海海洋大学教学成果特等奖

2014.12  上海海洋大学微课教学比赛 二等奖

2013.10  首届全国微课教学比赛上海市三等奖

2012.05  上海海洋大学科技成果二等奖

联系方式

地址：上海市沪城环路999号水产与生命学院

E-mail：dhniu@shou.edu.cn

（2024年3月更新）