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发布日期:2014-05-31
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许丹 副教授


许丹,女,博士,水产动物医学系副教授、硕士生导师。20106月获得中山大学海洋生物学博士学位;其中,2008.08-2009.08赴新加坡国立大学生物学系学习和工作一年;主要从事鱼类病原微生物致病机理和相关免疫学的研究

20107月入职上海海洋大学水生动物医学系,参与“东方学者”特聘教授吕利群教授科研团队,研究方向为水生动物传染病病理与分子免疫学


主持的科研项目

[1]2011.12-2013.12:上海海洋大学博士科研启动基金:草鱼呼肠弧病毒体内和体外感染中Dicer蛋白的作用;已结题。

[2]2012.06-2014.06:上海市教委青年教师培养资助计划草鱼呼肠孤病毒(GCRV)逃逸宿主细胞RNAi作用的分子机制;已结题。

[3]2012.01-2014.12:教育部博士点基金:草鱼呼肠孤病毒与宿主细胞相互作用的分子免疫机制;结题。

[4]2014.11-2015.12中科院淡水生态与生物技术国家重点实验室开放基金2015FB07鲫鱼单抗制备及抗疱疹病毒免疫应答的检测分析;结题。

参加的主要科研项目

[1]上海市教委:东方学者配套经费(2009.01-2011.12),排序第二;

[2]自然基金委国家自然科学基金草鱼呼肠孤病毒逃逸宿主RNAi抗病毒信号通路的机制研究2011.1-2013.12),排序第二;

[3]农业部现代农业产业技术体系渔药临床岗位专项经费:(2011.01-2015.12) ,排序第六。

发表论文及申请专利

[1]Dan Xu, Lang Song, Hao Wang, Xiaoyan Xu, Tu Wang , Liqun Lu*; Proteomic analysis revealed that cellular 1 Stress Granule pathway is disrupted by Grass carp reovirus infection. Fish & Shellfish Immunology, 2015, 44(2): 515-524.

[2]Dan Xu , Xupeng Hong, Haiquan Liu, Liqun Lu. Identification and pathogenicity of Vibrio parahaemolyticus isolates and immune responses of (Penaeus Litopenaeus) vannamei (Boone). Journal of Fish Diseases, DOI10.111/jfd.12441 2015.

[3]Xupeng Hong, Liqun Lu, Dan Xu*, Progress in research on acute hepatopancreatic necrosis disease (AHPND); Aquaculture International, 2015, DOI 10.1007/s10499-015-9948-x.

[4]Dan Xu, Siyao Xia, Patarida Podok, Weichen Qiu, Liqun Lu*; Characterization of IκBα, Rab21and Rac2 as innate immune genes during infection of Aeromonas hydrophila and Cyprinid herpesvirus 2 in crucian carp (Carassius auratus gibelio). Fish Pathology. 2016; 51:S7-S19.

[5]Dan Xu, Xiaobao Shen, Jiale Li, Liqun Lu*; Molecular cloning and immune responsive expression of a ribonuclease III orthologue involved in RNA interference, dicer, in grass carp Ctenopharyngodon idella. Journal of Fish Biology, 2013; 83:1234-1248.

[6]Dan Xu, Shuai Guo, Hongxu Xu, Tu Wang, Jiale Li and Liqun Lu*; Suppression of RNA Interference Pathway in vitro by Grass Carp Reovirus, VIROLOGICA SINICA, 2012, 27(2):109-119.

[7]Dan Xu; Jingguang Wei; Huachun Cui; Jie Gong; Yang Yan; Rongye Lai; Qiwei Qin*. Differential profiles of gene expression in Singapore grouper iridovirus (SGIV) infected grouper, Epinephelus coioides revealed by suppression subtractive hybridization (SSH) and DNA microarray. Journal of Fish Biology, 2010; 77: 341–360.

[8]Yanan Zhang, Hao Wang, Yan Li, Dan Xu, Liqun Lu*; Molecular cloning and expression analysis of the Ajuba gene of grass carp (Ctenopharyngodon idella) involved in cellular response to viral infection; Developmental & Comparative Immunology, 2015; 48(1):164-170.

[9]Patarida Podok, Lijuan Xu, Dan Xu, Liqun Lu*. Different expression profiles of Interleukin 11 (IL-11), Intelectin (ITLN) and Purine nucleoside phosphorylase 5a (PNP 5a) in crucian carp (Carassius auratus gibelio) in response to Cyprinid herpesvirus 2 and Aeromonas hydrophila. Fish Shellfish Immunol, 2014; 38(1): 65-73.

[10]Patarida Podok, Hao Wang, Lijuan Xu, Dan Xu, Liqun Lu*; Characterization of myeloid-specific peroxidase, keratin 8, and dual specificity phosphatase 1 as innate immune genes involved in the resistance of crucian carp (Carassius auratus gibelio) to Cyprinid herpesvirus 2 infection; Fish & Shellfish Immunology, 2014; 41(2): 531-540.

[11]Xiaobao Shen, Tu Wang, Dan Xu, Liqun Lu*;Proteomic identification, characterization and expression analysis of idella VDAC1 upregulated by grass carp reovirus infection. Fish & Shellfish Immunology, 2014;37:96-107.

[12]Hao Wang, Xiaobao Shen, Dan Xu, Liqun Lu*; Lipopolysaccharide-induced TNF-a factor in grass carp  (Ctenopharyngodon idella): Evidence for its involvement in antiviral innate immunity; Fish & Shellfish Immunology, 2013; 34(2): 538-545.

[13]Yongxing He, Hongxu Xu, Qian Yang, Dan Xu, Liqun Lu*.The use of an in vitro microneutralization assay to evaluate the potential of recombinant VP5 protein as an antigen for vaccinating against Grass carp reovirus. Virology Journal, 2011; 8:132

[14]Jinggeng Zhou; Jingguang Wei; Dan Xu; Qiwei Qin*. Cloning and expression of two hepcidin genes from grouper (Epinephelus tauvina) and their antipathogenic activity. Fish and Shellfish Immunology, 2011;30 (2):559-568.

[15]Jingguang Wei; Dan Xu; Jinggeng Zhou; Huachun Cui; Yang Yan; Zhengliang Ouyang; Jie Gong; Youhua Huang; Xiaohong Huang; Ping Zhang; Qiwei Qin*. Molecular cloning, characterization and expression analysis of a novel C-type lectin (Ec-CTL) in orange-spotted grouper, Epinephelus coioides. Fish and Shellfish Immunology. 2010, 28(1):178-186.

[16]王土,许丹,吕利群*;利用dsRNA快速测序技术在江西草鱼养殖区检测出两株GCRV病毒;上海海洋大学学报,20129):756-762

[17]刘兴旺,艾庆辉,徐玮,彭墨,许丹*;饲料中添加L-肉碱对大菱鲆生长及肝脏脂肪酸的影响;水产养殖,2012,3310):35-39

发明专利

[1]许丹,吕利群,郭帅,王土;一种防治黄颡鱼出血性水肿病的复合免疫增强剂及其制备方法和应用;发明专利号:201110175846.5

讲授的主要课程

[1]《微生物学》,本科生专业基础必修课;

[2]《免疫学》,本科生专业必修课;

[3]《水生动物公共卫生学》,本科生专业选修课;

承担的实践性教学

[1]《微生物学(实验)》,本科生专业基础必修课;

[2]《水生动物免疫学(实验)》,本科生专业选修课;

[3]《免疫学(实验)》,本科生专业必修课;

[4]指导本科毕业论文累计12人次;

[5]20146月:2012级水生动物医学专业短学期渔药调查实;20156月;2014级水产养殖短学期专业认知实习;20166月:2015级水产养殖短学期专业认知实习;

参与的教学研究课题

[1]2009/12-2011/12,上海海洋大学085建设,《海洋微生物学》课程改革项目,第二参加人。

发表的教学研究论文

[1]许丹;吕利群;杨金龙;水产养殖专业微生物教学的改革与实践;安徽农业科学,2013219149-9150

[2]许丹;吕利群;《水生动物传染病学》课程建设研究;安徽农业科学,201422):7683-7684

获得的表彰/奖励

[1]2014/12,《微生物学》微课比赛获2014年度校教学比赛二等奖

[2]2013/06, 上海海洋大学科学成果二等奖:草鱼呼肠孤病毒疫苗开发相关技术研究;排名第五。

联系方式

地址:上海市临港新城沪城环路999号水产与生命学院181信箱

邮编:201306

E-mail: dxu@shou.edu.cn

电话:021-61900433


20181月更新)