牛东红，博士，教授，博士生导师，水产与生命学院水产种质与育种系主任。中国水产学会盐碱水养殖专业委员会委员。2001年毕业于河北大学生物学专业，理学学士；2004年毕业于河北大学水生生物学专业，理学硕士；2009年毕业于上海海洋大学水产养殖学专业，博士学位。曾于美国Auburn University农学院水产系遗传学实验室进行留学访问。先后主持国家自然科学基金项目3项、国家重点研发项目任务4项，培育国家水产新品种1个。获得上海海洋科学技术奖一等奖，自然资源科学技术奖二等奖以及全国高校教师教学创新大赛上海市二等奖等科研和教学奖励。

主要研究方向

[1] 海洋贝类环境适应性进化机制。

[2] 海洋贝类耐盐耐高温等抗逆性状的调控机制。

[3] 海洋贝类分子育种关键技术探究与新品种遗传选育。

主要承担的国家级和省部级科研项目

[1] 2025.5-2028.05 国家重点研发计划“东海滩涂碳汇型生态高效养殖关键技术与装备”项目

[2] 2024.1-2027.12国家自然科学基金面上项目“脯氨酸提高缢蛏耐高盐性能的关键信号通路和作用机制”

[3] 2023.12-2027.12国家重点研发计划“盐碱水土一体化循环利用与生态改良渔业模式”项目

[4] 2021.1-2025.12 上海市水产动物良种创制与绿色养殖协同创新中心项目

[5] 2019.11-2022.12国家重点研发计划“海水池塘和盐碱水域生态工程化养殖技术与模式”项目

[6] 2019.11-2022.12国家重点研发计划“滩涂增养殖技术与生态农牧化新模式”项目

[7] 2018.01-2020.12 水产双一流学科建设项目“水产种质资源研究与支撑平台能力提升”

[8] 2015.01-2018.12 国家自然科学基金面上项目 “缢蛏幼虫变态过程IGFBPs基因调控的分子基础研究”

[9] 2012.01-2014.12 国家自然科学青年基金 “缢蛏生长相关基因SNPs和CNPs与生长性状的关联分析”

[10] 2012.01-2015.12 国家“863”计划项目“主要养殖双壳贝类良种培育”

近五年主要发表论文

[1] Ruiqi Liu^#, Kai Ye^#, Na Zhang, Tianyu Zhan, Donghong Niu*. Proline enhances immune defense and mitigates hypersalinity stress in the razor clam Sinonovacula constricta. Fish and Shellfish Immunology, 2026,168 :110935.

[2] Zihan Lin, Honglei Wang, Geqi Gao, Hongtao Nie, Kai Ye, Donghong Niu*, Jiale Li. Multi-omics approaches provide insights into adaptation to low salinity of intertidal clams. Marine Environmental Research, 2025, 211:107467.

[3] Kai Ye, Ruiqi Liu, Tianyu Zhan, Si Chen, Jiamei Yu, Donghong Niu *. The heat-resistant capability analysis of two populations of Sinonovacula constricta under thermal stress. Journal of Thermal Biology, 2025,130:104164.

[4] Yuting Han^#, Kai Ye^#, Geqi Gao, Jinxu Guo, Ming Shan, Donghong Niu*. Integrated analysis of antioxidant defense and energy metabolism in the gills of Sinonovacula constricta under hyposalinity stress, Comparative Biochemistry and Physiology Part A, 2025,310:111932.

[5] Min Yang, Yuting Han, Yujie Chang, Chengbo Li, Donghong Niu*. Transcriptomic and metabolomic analyses reveal response mechanisms of Sinonovacula constricta to saline-alkalinity stresses. Marine Biotechnology, 2025, 27(2): 68.

[6] 张娜, 刘瑞琦, 詹天宇, 金凯, 牛东红*. 脯氨酸对高盐下缢蛏鳃组织结构,抗氧化能力及细胞凋亡的影响. 广东海洋大学学报, 2025, 45 (2): 27-34.

[7] 陆阳, 刘涛, 孙梦颖, 沈和定*, 牛东红*. 低氧胁迫下缢蛏鳃转录组分析及能量代谢响应. 南方农业学报, 2025, 56(6): 1859-1868.

[8] 李春，刘琦，陈宇宽，袁立，牛东红*. 高温对缢蛏生理代谢和抗氧化水平的影响.水产学报, 2025, 49(6):069107.

[9] Geqi Gao^#, Dong Yang^#, Linyun Hu, Liang Jia*, Donghong Niu*. Molecular and physiological characterizations of razor clam (Sinonovacula constricta) aquaporin genes AQP4 and AQP10 in response to low-salinity tolerance. Comparative Biochemistry and Physiology A, 2025, 303: 111827

[10] Yihua Chen, Zhengyu Shao, Guolong Zhou, Hu Ang, Hongbing Ding, Haoyu Li, Zhiguo Dong*, Donghong Niu*, Jiale Li. Salinity tolerance assessment of different families of the razor clam Sinonovacula constricta using physiological traits[J]. Aquaculture, 2025, 595:741494.

[11] Tao Liu, Yang Lu, Mengying Sun, Heding Shen*, Donghong Niu*. Effects of acute hypoxia and reoxygenation on histological structure. Fish and Shellfish Immunology.2024,145: 109310

[12] Yihua Chen，Min Deng，Zhiguo Dong, Yifeng Li, Donghong Niu*. Function of taurine and its synthesis-related genes in hypertonic regulation of Sinonovacula constricta. Comparative Biochemistry and Physiology Part A. 2024, 287:111536

[13] Yuting Han, Beibei Li, Yifeng Li, Donghong Niu*. The inhibitory effects of rna-interference-mediated guanylate cyclase knockdown on larval metamorphosis and early progeny growth of razor clam. Genes, 2023, 14(2):459

[14] 陈义华,牛东红*,董志国,李家乐. 缢蛏耐高盐性能及其与生长性状的相关性分析. 海洋科学, 2022, 46(10):51-58.

[15] Yihua Chen, Xinin Du, Zhiguo Dong, Yifeng Li, Donghong Niu*. Heritability estimation of high salt tolerance in razor clam (Sinonovacula constricta) Aquaculture 2022: 738423

[16] Yihua Chen, Yukuan Chen, Liang Tao, Xinxin Du, Zhiguo Dong*, Donghong Niu*, Jiale Li*. Genetic parameters and genotype by environment interaction for growth traits of razor clam Sinonovacula constricta, from outdoor pond and semi-natural environment. Aquaculture Reports,2022,24:101173

[17] Yizhen Wang, Yuting Han, Yanhui Wang, Min Lv, Yifeng Li, Donghong Niu *. Expression of p38MAPK and its regulation of apoptosis under high temperature stress in the razor clam Sinonovacula constricta. Fish and Shellfish Immunology, 2022,12: 288-297

[18] Yihua Chen, Haoyu Li, Hongbing Ding, Zhiguo Dong, Donghong Niu*, Jiale Li*. Heritability estimation and path analysis for growth traits of the razor clam Sinonovacula constricta under high salinity. Aquaculture, 2021(545):737175

[19] Yinghan Wu, Yi Zheng, Yan Li, Yifeng Li, Donghong Niu*. Two fibrinogen-related proteins (freps) in the razor clam (Sinonovacula constricta ) with a broad recognition spectrum and bacteria agglutination activity. Developmental & Comparative Immunology, 2021,121.104075

[20] Yan Li, Donghong Niu*, Yinghan Wu, Zhiguo Dong, Jiale Li*.  Integrated analysis of transcriptomic and metabolomic data to evaluate responses to hypersalinity stress in the gill of the razor clam (Sinonovacula constricta). Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2021, 38(4):100793. 3

[21] Yihua Chen^#, Bo Ye^#, Donghong Niu*, Jiale Li. Changes in metabolism and immunity in response to acute salinity stress in Chinese razor clams from different regions. Aquaculture Reports, 2021(19),100624

[22] Zhi Li^#, Maoxiao Peng^#, Deborah Mary Power, Donghong Niu*, Zhiguo Dong, Jiale Li*. RNAi-mediated knock-down of the dopamine beta-hydroxylase gene changes growth of razor clams. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2021, (252):110534.

获奖情况

2025.11  自然资源科学技术奖 二等奖  

2025.05  上海海洋科学技术奖 一等奖

2023.09  上海海洋大学育才奖

2022.08  上海海洋科学技术奖 一等奖

2021.11  神农中华农业科技奖 优秀创新团队

2022.08  全国高校教师教学创新大赛 上海市二等奖

2021.12  全国高校教师教学创新大赛 校级一等奖

2021.07  上海海洋大学优秀研究生指导教师

2019.12  汉宝奖学金优秀青年教师奖

2019.12  上海海洋大学教学成果特等奖

2014.12  上海海洋大学微课教学比赛 二等奖

2013.10  首届全国微课教学比赛上海市三等奖

2012.05  上海海洋大学科技成果二等奖

联系方式

地址：上海市沪城环路999号水产与生命学院

E-mail：dhniu@shou.edu.cn